Keys To Managing Severe Onychomycosis

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Myron Bodman, DPM

26. Elewski BE, Ghannoum MA, Mayser P, et al. Efficacy, safety and tolerability of topical terbinafine nail solution in patients with mild-to-moderate toenail onychomycosis: results from three randomized studies using double-blind vehicle-controlled and open-label active-controlled designs. J Eur Acad Dermatol Venereol. 2011 Dec 20. Epub ahead of print.
27. Gupta AK, Simpson FC. New therapeutic options for onychomycosis. Expert Opin Pharmacother. 2012 Jun;13(8):1131-42.
28. Formula-3 PI. Available at .
29. Fungoid Tincture PI. Available at
30. Malay DS, Yi S, Borowsky P, et al. Efficacy of debridement alone versus debridement combined with topical antifungal nail lacquer for the treatment of pedal onychomycosis: a randomized, controlled trial. J Foot Ankle Surg. 2009;48(3):294-308.
31. Grover C, Bansal S, Nanda S, et al. Combination of surgical avulsion and topical therapy for single nail onychomycosis: a randomized controlled trial. Br J Dermatol. 2007;157(2):364-8.
32. Pandhi D, Verma P. Nail avulsion: Indications and methods (surgical nail avulsion). Indian J Dermatol Venereol Leprol. 2012;78(3):299-308.
33. South DA, Farber EM. Urea ointment in the nonsurgical avulsion of nail dystrophies: A reappraisal. Cutis. 1980; 25(6):609-12.
34. Averill RW, Scher RK. Simplified nail taping with urea ointment for nonsurgical nail avulsion. Cutis. 1986;38(4):231-3.
35. Neev J, Nelson JS, Critelli M, et al. Ablation of human nail by pulsed lasers. Lasers Surg Med. 1997;21(2):186-92.
36. Landsman AS, Robbins AH. Treatment of mild, moderate, and severe onychomycosis using 870- and 930-nm light exposure: some follow-up observations at 270 days. J Am Podiatr Med Assoc. 2012; 102(2):169-71.
37. United States Food and Drug administration medical device approval (K103626). Available at .
38. Hees H, Raulin C, Bäumler W. Laser treatment of onychomycosis: an in vitro pilot study. J Dtsch Dermatol Ges. 2012 Dec;10(12):913-7.
39. Bodman MA, Blazer M, Caldwell, B. Unpublished data, Cleveland Foot and Ankle Clinic of the Kent State University College of Podiatric Medicine, Independence, Ohio.
40. Kimura U, Takeuchi K, Kinoshita A, et al. Treating onychomycoses of the toenail: clinical efficacy of the sub-millisecond 1,064 nm Nd: YAG laser using a 5 mm spot diameter. J Drugs Dermatol. 2012;11(4):496-504.
41. Zhang RN, Wang DK, Zhuo FL, et al. Long-pulse Nd:YAG 1064-nm laser treatment for onychomycosis. Chin Med J. 2012;125(18):3288-91.
42. Gupta AK, Simpson FC. New therapeutic options for onychomycosis. Expert Opin Pharmacother. 2012;13(8):1131-42.
43. Warshaw EM, Bowman T, Bodman MA, et al. Satisfaction with onychomycosis treatment. Pulse versus continuous dosing. J Am Podiatr Med Assoc. 2003;93(5):373-9.

   For further reading, see “Roundtable Insights On Treating Onychomycosis” in the May 2011 issue of Podiatry Today or “Could Efinaconazole 10% Have An Impact For Onychomycosis?” in the February 2013 issue.

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