How Biofilm Affects Healing In Diabetic Foot Wounds

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Rhonda Cornell, DPM

   Another viable treatment option may be the use of ultrasound debridement on the chronic wound. Researchers have suggested that ultrasound disrupts the quorum sensing that occurs within biofilms, thereby leading to decreased coordinated virulence.7 Although this treatment option has potential and would be a breakthrough for treating biofilm on chronic wounds, further studies are still needed to demonstrate the efficacy of ultrasonic debridement on the biofilm.

In Conclusion

   As the number of patients with diabetes continues to rise in the U.S., so too will the number of diabetic complications such as foot ulcers. It is becoming more apparent that the profession needs to pay greater attention to the role of biofilm in chronic wounds. Methods of biofilm eradication can encourage healing in a timely manner and avoid secondary complications, including infection, hospitalization and amputation in our high-risk diabetic population.

Dr. Cornell is currently doing a Fellowship in Diabetic Limb Salvage at Georgetown University Hospital in Washington, D.C.

Dr. Steinberg is an Assistant Professor in the Department of Plastic Surgery at the Georgetown University School of Medicine in Washington, D.C. Dr. Steinberg is a Fellow of the American College of Foot and Ankle Surgeons.


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