Exploring The Potential Of Acellular Dermis Grafts For Wound Healing And Soft Tissue Repair
- Volume 25 - Issue 12 - December 2012
- 12448 reads
- 0 comments
Acellular dermis grafts are useful and versatile tools to have in one’s surgical armamentarium. A thorough understanding of the basic science of wound and graft healing, particularly how the grafts serve as scaffolds for new tissue ingrowth, enhances the ability to use these grafts more effectively. Although still very useful in wound healing, additional applications of acellular dermis grafts including tendon repair, ligament reconstruction, soft tissue supplementation and joint resurfacing should be given due consideration in surgical planning to optimize patient outcomes.
Dr. Branch is in private practice with several offices in the Atlanta area. He is board certified in both foot surgery and reconstructive rearfoot and ankle surgery.
1. Beniker D, McQuillan D, Livesey S, et al. The use of acellular dermal matrix as a scaffold for periosteum replacement. Orthopedics. 2003; 26(5):591-6.
2. Barber FA, McGarry JE, Herbert MA. A biomechanical study of Achilles tendon repair augmentation using GraftJacket® matrix. Foot and Ankle International. 23(4):329-33, 2008.
3. Liden BA, Simmons M. Histologic evaluation of a 6-month GraftJacket® matrix biopsy used for Achilles tendon augmentation. J Amer Pod Med Assoc. 2009; 99(2):104-7.
4. Brady C. Ankle stabilization surgical technique using the split peroneus longus tendon (surgical protocol). Available at
5. Lee MS. GraftJacket augmentation of chronic Achilles tendon ruptures. Orthopedics. 2004; 27(1 Suppl):s151-3.
6. Weil LJ, Kurvilla B, Bergman D, Cain JD,Fridman R. The use of Pegasus OrthoAdapt™ Bioimplant in lateral ankle stabilization surgery. Available at http://www.weil4feet.com .
7. Grove JR, Hardy MA. Autograft, allograft, and xenograft options in the treatment of neglected Achilles tendon ruptures: A historical review with illustration of surgical repair. Foot Ankle J. 2008; 1(5):1.
8. Kummer FJ, Iesaka K. The role of graft materials in suture augmentation for tendon repairs and reattachment. J Biomed Mater Res B Appl Biomater. 2005; 74(2):789-91.
9. Malcarney HI, Bonar F, Murrell GA. Early inflammatory reaction after rotator cuff repair with porcine small intestine submucosal implant. Am J Sports Med. 2005; 33(6):907-911.
10. Roukis TS, Kovacevich LC. Foreign body reaction to a xenograft biological tissue scaffold and concominant infection: a report of two cases. Poster presentation at the Meeting of the American College of Foot and Ankle Surgeons, 2007.
11. Berlett GC, Hyer CF, Lee TF, et al. Interpositional arthroplasty of the first MTP joint using a regenerative tissue matrix for the treatment of advanced hallux rigidus. Foot Ankle. 2008; 29(1):10-21.
12. Branch JP. A tendon graft weave using an acellular dermal matrix for repair of the achilles tendon and other foot and ankle tendons. J Foot and Ankle Surg. 2011; 50 (2):242–250.
13. Coons DA, Barber FA. Tendon graft substitutes – Rotator cuff patches. Sports Med Arthrosc Rev. 2006; 14(3):185-90.
14. Malcarney HI, Bonar F, Murrell GA. Early inflammatory reaction after rotator cuff repair with porcine small intestine submucosal implant. Am J Sports Med. 2005; 33(6):907-911.
15. DeFranzo AJ, Argenta LC, Marks MW, Molnar JA, David LR, Webb LX, Ward LX, Ward WG, Teasdall RG. The use of vacuum-assisted closure therapy for the treatment of lower-extremity wounds with exposed bone. Plast Reconstr Surg. 2001; 108(5):1184-91.
16. DeLange MY, Schaasfoort RA, Obdeijn MC, van Der Werff JFA, Nicolai JPA. Vacuum-assisted closure: indications and clinical experience. Eur J Plast Surg. 2000; 23(4):178-82.
17. Repta R, Ford R, Hoberman L, Rechner B. The use of negative-pressure therapy and skin grafting in the treatment of soft tissue defects over the Achilles tendon. Ann Plast Surg. 2005; 55(4):367-70.