Can Copper Help Prevent Lower Extremity Complications In Patients With Diabetes?

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Author(s): 
Gary M. Rothenberg, DPM, CDE, CWS

   Dr. Rothenberg is the Director of Residency Training and is an Attending Podiatrist with the Miami Veterans Affairs Healthcare System.

References

1. Borkow G, Gabbay J. Putting copper into action: copper-impregnated products with potent biocidal activities. FASEB J. 2004;18(14):1728-30.
2. Philips N, Hwang H, Chauhan S, Leonardi D, Gonzalez S. Stimulation of cell proliferation and expression of matrixmetalloproteinase-1 and interleukin-8 genes in dermal fibroblasts by copper. Connect Tissue Res. 2010;51(3):224-9.
3. Mehtar S, Wiid I, Todorov SD. The antimicrobial activity of copper and copper alloys against nosocomial pathogens and Mycobacterium tuberculosis isolated from healthcare facilities in the Western Cape: an in-vitro study. J Hosp Infect. 2008;68(1):45-51
4. Borkow G, Gabbay J, Dardik R, et al. Molecular mechanisms of enhanced wound healing by copper oxide impregnated dressings. Wound Repair Regen. 2010;18(2):266-75.
5. Zatcoff R, Smith M, Borkow G. Treatment of tinea pedis with socks containing copper-oxide impregnated fibers. Foot (Edinb). 2008;18(3):136-41.
6. Borkow G, Zatcoff RC, Gabbay J. Reducing the risk of skin pathologies in diabetics by using copper impregnated socks. Med Hypotheses. 2009;73(6):883-6.

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