Is Inhaled Insulin A Viable Alternative For Patients With Diabetes?

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Patients with diabetes can use Exubera (Pfizer) to inhale insulin. As the authors note, insulin is absorbed more rapidly through inhalation than through subcutaneous injection.
One study looked at patients between 35 and 80 with type 2 diabetes. Researchers discovered hyperglycemia was slightly lower in those who inhaled insulin before a meal and also injected insulin before bedtime.
Is Inhaled Insulin A Viable Alternative For Patients With Diabetes?
By Jennifer Pahira and John S. Steinberg, DPM

1. Nektar Therapeutics.
2. Weiss SR, et. al. Inhaled Insulin Provides Improved Glycemic Control in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Oral Agents. Archives of Internal Medicine 163(19). 2003.
3. Hollander PA, et. al. Efficacy and Safety of Inhaled Insulin (Exubera) Compared With Subcutaneous Insulin Therapy in Patients With Type 2 Diabetes. Diabetes Care. 27:2356-2362, 2004.
Additional References
4. Skyler JS, et. al. American Diabetes Association. Diabetes Care 28:1630–1635, 2005.
5. DeNoon D. WebMD Medical News.
6. International Diabetes Federation.
7. Walsh J. Will It Really Take Your Breath Away? 2006.
8. Medical News Today. Inhaled insulin controls diabetes over long term. MediLexicon International Ltd. 2004.
9. D’Arrigo T. Inhaled Insulin is on The Way. Diabetes Watch, 2006.

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