How To Recognize Skin Disorders In Diabetic Patients

Start Page: 14
Keep in mind that necrobiosis lipoidica diabeticorum (NLD) lesions appear earlier in life (30 years) in the diabetic population than in the non-diabetic population (41 years).
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Author(s): 
By Anthony Yung, DPM

In Conclusion
There are many manifestations of diabetes in the skin, yet there is little information on the pathophysiology of the skin disorders discussed above. Exactly why do these disorders have greater incidence in the diabetic population? In the coming years, perhaps a common thread in the pathology of these disorders may be found and more effective treatments may be elicited.
For now, being able to recognize the skin manifestations and their natural history will allow us to educate patients and select appropriate treatment courses.

Dr. Yung is a first-year resident at the University of Texas Health Science Center in San Antonio.
Dr. Steinberg (pictured) is an Assistant Professor in the Department of Orthopaedics/Podiatry Service at the University of Texas Health Science Center.




References:

References
1. Muller SA, Winkelmann RK: Dermatologic disorders associated with diabetes mellitus. Mayo Clin Proc 41:689-703, 1966.

2. Lowitt, MH and Dover, JS. Necrobiosis Lipoidica. J. Am Acad Dermatol, 1992, 25:735-748.

3. Muller SA, Winkelmann RK Necrobiosis Lipoidica: Histopathologic study of 98 cases. Arch Dermatol. 1966 94:1-10.

4. Tkach JR. Platlet-inhibitiaon therapy of ulcerated necrobiosis lipoidica diabeticorum. Dermatol Allergy 5:9-12, 1982.

5. Allen GE, Diabetes mellitus and the Skin. Practitioner 203: 189, 1969.

6. Bauer M and Levan NE, Diabetic dermangiopathy. A spectrum including pretibial pigmented patches and necrobiosis lipoidca diabeticorum. Br J Dermatol, 1970. 83:528-535.

7. Aagenaes O, Moe H. Light and electron microscopy study of skin capillaries of diabetics. Diabetes 1961 10: 253-259.

8. Lithner F. Cutaneous reactions of the extremities of diabetic to local thermal trauma. Acta Med Scand, 1975. 198: 319-325.

9. Bodman M, Frideman S and Clifford L. Bullosis diabeticorum. A report of two cases with a review of the literature. JAPMA 1991 81: 561-563.

10. Rosenbloom AL, Silverstien JH, Lezotte D, et. al. Limited Joint Mobility in Childhood Diabetes Mellitus Indicates Increased Risk For Microvascular Disease NEJM 305: 191-194.

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