Assessing The Potential Wound Healing Abilities Of Ciclopirox

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Assessing The Potential Wound Healing Abilities Of Ciclopirox
Here one can see severe vesicular tinea pedis. When this type of fungal infection — with major involvement and blisters — is present among patients with diabetes, it can develop into a chronic ulcer.
Here is an ulcer with tinea pedis. This ulcer developed from a previously fungally infected area in a patient with diabetes.
Assessing The Potential Wound Healing Abilities Of Ciclopirox
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Author(s): 
By Gary L. Dockery, DPM, FACFAS
FASEB J [serial online] February 19, 2003. Available at: http://www.fasebj.org/cgi/doi/10.1096/fj.02-0586fje. Accessed April 30, 2004.
19. Rolfs A, Kvietikova I, Gassmann M, Wenger RH: Oxygen-regulated transferring expression is mediated by hypoxia-inducible factor-1. J Biol Chem. 1997;272:20055-20062. Cited by: Linden T, Katschinski DM, Eckhardt K, Scheid A, Pagel H, Wenger RH: The antimycotic ciclopirox olamine induces HIF-1a stability, VEGF expression, and angiogenesis. FASEB J [serial online] February 19, 2003. Available at: http://www.fasebj.org/cgi/doi/10.1096/fj.02-0586fje. Accessed April 30, 2004.
20. Keberle H: The biochemistry of desferrioxamine and its relation to iron metabolism. Ann N Y Acad Sci. 1964;119:758-768. Cited by: Linden T, Katschinski DM, Eckhardt K, Scheid A, Pagel H, Wenger RH: The antimycotic ciclopirox olamine induces HIF-1a stability, VEGF expression, and angiogenesis. FASEB J [serial online] February 19, 2003. Available at: http://www.fasebj.org/cgi/doi/10.1096/fj.02-0586fje. Accessed April 30, 2004.
21. Page JC, Abramson C, Lee WL, McCarthy DJ, McGinley KJ, Williams D: Diagnosis and treatment of tinea pedis: a review and update. J Amer Podiatr Med Assoc. 1991;81(6):304-316.
22. Abramson C: A New Look at Dermatophytosis and Atopy. Podiatric Dermatology; DJ McCarthy, RA Montgomery, eds. Williams & Wilkins. Baltimore, Maryland; 1986.
23. American Diabetes Association: Diabetes Facts: The Dangerous Toll of Diabetes. Alexandria, Virginia. 1996.
24. Reiber GE, Boyko EJ, Smith DG: Lower extremity foot ulcers and amputations in diabetes. Diabetes in America, 2nd Edition. Harris MI, Cowie CC, Stern MP, Boyko EJ, Reiber GE, Bennett PH, eds. U.S. Government Printing Office. Washington, DC; 1995:409-428.
25. Kapellen TM, Galler A, Kiess W: Higher frequency of paronychia (nail bed infections) in pediatric and adolescent patients with type 1 diabetes mellitus than in non-diabetic peers. J Pediatr Endocrinol Metab. 2003;16(5):751-758.
26. Dockery GL: Fungal, Skin and Nail Infections. Cutaneous Disorders of the Lower Extremity. WB Saunders Co., 1997: (Chapter 6)52-65.
27. Aye M, Masson EA: Dermatological care of the diabetic foot. Am J Clin Dermatol. 2002;3(7):463-474.
28. Gupta AK: Ciclopirox gel: an update. Int J Dermatol. 2003;42(Suppl):1-2.


























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