Assessing The Potential Wound Healing Abilities Of Ciclopirox

Start Page: 20
Assessing The Potential Wound Healing Abilities Of Ciclopirox
Here one can see severe vesicular tinea pedis. When this type of fungal infection — with major involvement and blisters — is present among patients with diabetes, it can develop into a chronic ulcer.
Here is an ulcer with tinea pedis. This ulcer developed from a previously fungally infected area in a patient with diabetes.
Assessing The Potential Wound Healing Abilities Of Ciclopirox
26
Author(s): 
By Gary L. Dockery, DPM, FACFAS
Available at: http://www.fasebj.org/cgi/doi/10.1096/fj.02-0586fje. Accessed April 30, 2004.
12. Supp DM, Supp AP, Bell SM, Boyce ST: Enhanced vascularization of cultured skin substitutes genetically modified to overexpress vascular endothelial growth factor. J Invest Dermatol. 2000;114:5-13. Cited by: Linden T, Katschinski DM, Eckhardt K, Scheid A, Pagel H, Wenger RH: The antimycotic ciclopirox olamine induces HIF-1a stability, VEGF expression, and angiogenesis. FASEB J [serial online] February 19, 2003. Available at: http://www.fasebj.org/cgi/doi/10.1096/fj.02-0586fje. Accessed April 30, 2004.
13. Deodato B, Arsic N, Zentilin L, Galeano M, Santoro D, Torre V, et al: Recombinant AAV vector encoding human VEGF165 enhances wound healing. Gene Ther. 2002;9:777-785. Cited by: Linden T, Katschinski DM, Eckhardt K, Scheid A, Pagel H, Wenger RH: The antimycotic ciclopirox olamine induces HIF-1a stability, VEGF expression, and angiogenesis. FASEB J [serial online] February 19, 2003. Available at: http://www.fasebj.org/cgi/doi/10.1096/fj.02-0586fje. Accessed April 30, 2004.
14. Romano Di Peppe S, Mangoni A, Zambruno G, Spinetti G, Melillo G, Napolitano M, et al: Adenovirus-mediated VEGF165 gene transfer enhances wound healing by promoting angiogenesis in CD1 diabetic mice. Gene Ther. 2002;9:1271-1277. Cited by: Linden T, Katschinski DM, Eckhardt K, Scheid A, Pagel H, Wenger RH: The antimycotic ciclopirox olamine induces HIF-1a stability, VEGF expression, and angiogenesis. FASEB J [serial online] February 19, 2003. Available at: http://www.fasebj.org/cgi/doi/10.1096/fj.02-0586fje. Accessed April 30, 2004.
15. Kallio PJ, Okamoto K, O’Brien S, Carrero P, Makino Y, Tanaka H, et al: Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1a. EMBO J. 1998; 17:6573-6586. Cited by: Linden T, Katschinski DM, Eckhardt K, Scheid A, Pagel H, Wenger RH: The antimycotic ciclopirox olamine induces HIF-1a stability, VEGF expression, and angiogenesis. FASEB J [serial online] February 19, 2003. Available at: http://www.fasebj.org/cgi/doi/10.1096/fj.02-0586fje. Accessed April 30, 2004.
16. Wang GL, Semenza GL: Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA-binding activity: implications for models of hypoxia signal transduction. Blood. 1993;82:3610-3615. Cited by: Linden T, Katschinski DM, Eckhardt K, Scheid A, Pagel H, Wenger RH: The antimycotic ciclopirox olamine induces HIF-1a stability, VEGF expression, and angiogenesis. FASEB J [serial online] February 19, 2003. Available at: http://www.fasebj.org/cgi/doi/10.1096/fj.02-0586fje. Accessed April 30, 2004.
17. Gleadle JM, Ebert BL, Firth JD, Ratcliffe PJ: Regulation of angiogenic growth factor expression by hypoxia, transition metals, and chelating agents. Am J Physiol. 1995;268:C1362-C1368. Cited by: Linden T, Katschinski DM, Eckhardt K, Scheid A, Pagel H, Wenger RH: The antimycotic ciclopirox olamine induces HIF-1a stability, VEGF expression, and angiogenesis. FASEB J [serial online] February 19, 2003. Available at: http://www.fasebj.org/cgi/doi/10.1096/fj.02-0586fje. Accessed April 30, 2004.
18. Wanner RM, Spielmann P, Stroka DM, Camenisch G, Camenisch I, Scheid A, et al: Epolones induce erythropoietin expression via hypoxia-inducible factor-1a activation. Blood. 2000;96:1558-1565. Cited by: Linden T, Katschinski DM, Eckhardt K, Scheid A, Pagel H, Wenger RH: The antimycotic ciclopirox olamine induces HIF-1a stability, VEGF expression, and angiogenesis.
image description image description


Post new comment

  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.

More information about formatting options

Image CAPTCHA
Enter the characters shown in the image.