Exploring Alternative Treatment For Resistant Warts

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This otherwise healthy patient inappropriately applied OTC 40% salicylic acid to his warts and presented with substantial pain caused by ulceration of the skin that was well beyond the viral tissue margins.
Here one can see a wart before treatment with 5-fluorouracil.
Here you can see the characteristic superficial ulceration that usually occurs between the fourth and tenth week of treatment with 5-fluorouracil. This ulceration is desirable as it indicates destruction of the lesion.
Here one can see the interruption of skin lines along with acanthosis, hyperkeratosis and small dark pinpoint dots representing thrombosed capillaries.
By Robert Salk, DPM, Kirk Grogan, DPM, Thomas Chang, DPM, and Walter D’Costa, DPM

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Additional References

14. Stehr-Green PA, Hewer P, Meekin GE, et al. The aetiology and risk factors for warts among poultry processing workers. Int J Epidemiol. 1993;22:294-298.

15. Keefe M, Al-Ghamdi A, Coggon D, et al. Cutaneous warts in butchers. Br J Dermatol. 1994;130:9-14.

16. Gibbs S, Harvey I. Local treatments for cutaneous warts: systematic review. Br Medical Journal. 2002:325:461-464.

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